The series "Off the Hook" is a British comedy about the lives of university freshmen. A guy named Danny, who was an outsider in high school, dreams of leaving his past behind and embracing a fresh start. However, an unpleasant surprise awaits him in the student campus. It turns out that his new roommate, Shane, with whom they once sat at the same desk, is a slacker, partygoer, and the "worst best friend in the world." In the neighboring block, there live the feisty beauty Scarlett and the perpetually gloomy Fred.