The anthology series is a heart-wrenching collection of the most sinister, unsettling, and blood-chilling stories. It is an adaptation of the best manga by the cult writer and master of shadows, Junji Ito. The anime anthology includes over 20 works by the mysterious genius. The plots of the episodes are not connected to each other. They are based on Ito's manga, particularly the stories of Tomie - an immortal girl who can make men kill for her - and Soiti, an ambitious youth who delves into dark magic.