The series "Dope Girls" is a criminal historical drama about the creation of an underground nightclub in Soho. The events take place in 1920s London. Kate Mayrick, a single mother who has spent her best years working hard, taking care of her children, and going to church, grows tired of constant poverty and religious piety. She invests all her savings into buying and renovating a bar. Kate's regular customers become soldiers with post-traumatic stress disorder, who suffered during the First World War.