The series "Best Interests" is a drama about the story of a family forced to make an incredibly difficult choice. Andrew and Nikki, like any normal parents, love their daughter Marnie unconditionally. However, doctors give the girl a terrifying diagnosis. Despite all their efforts, there is no progress in her treatment, and the family is advised to let Marnie rest, allowing her to live for as long as fate allows. However, the parents are not willing to give up. They are ready to make any sacrifices to prolong their child's life.