The story revolves around a talented doctor named Ziya, who is ready to take on the most challenging medical cases. While other doctors helplessly throw up their hands, Ziya never gives up. He wants to revolutionize medicine and show humanity new ways to treat many serious illnesses. Deciding to move from his hometown of Bursa to the bustling city of Istanbul, Ziya encounters a former colleague who is equally successful and ambitious. They decide to work together.