Carskaya privivka – The TV series "Royal Vaccination" is a Russian historical drama about the first mass vaccination in the Russian Empire. The events take place in the 18th century during the reign of Empress Catherine the Great. In 1768, dangerous outbreaks of a new disease, smallpox, occur throughout Europe. Fortunately, scientists manage to invent a vaccine against this plague. However, in order for it to take effect, they need to find a way to convince the simple and uneducated people to get vaccinated. And in Russia, peasant uprisings are already taking place...